One of only three proton therapy centers on the entire West Coast — built from the ground up, in the middle of San Francisco's most ambitious redevelopment, on top of a basement vault requiring mass concrete radiation shielding and structural tolerances precise enough to guide a beam that targets individual tumor cells. Above it: UCSF clinical space, a life sciences incubator, and a façade designed by Herzog & de Meuron.

At the heart of the Potrero Power Station redevelopment, one of San Francisco's most significant urban transformation projects, Webcor is delivering a clinical and life sciences building that is anything but typical.

Below grade sits a Proton Therapy Center, one of only three such facilities on the West Coast and among the most technically demanding building types in healthcare construction. Proton therapy uses a focused beam to target cancer cells with greater precision and less damage to surrounding tissue than conventional radiation treatment. Delivering the infrastructure to support it requires exact structural tolerances, mass concrete for radiation shielding, and miles of underground conduit for utility feeds, all engineered with future equipment removal and replacement in mind.

Rising from that base is a multi-story structure housing UCSF clinical space on floors two through five, with a life sciences incubator occupying floors six through eight. The project is delivered through a P3 model on UCSF-owned land, with Associate Capital as developer, and designed by an exceptional team including Herzog & de Meuron, Stantec, and Flad, with structural engineering by MKA and MEP engineering by Interface Engineering.

Webcor entered the project late in preconstruction, inheriting an established subcontractor base and absorbing roughly 11 bought-out scopes, including Webcor Concrete, Southland, Cupertino, and the Malcolm Drilling/Silverado JV. The Hitachi-supplied proton therapy equipment sets the tolerance requirements that drive every structural decision in the building, making coordination between design, construction, and specialty vendors a defining challenge from day one. Construction is underway, with completion expected in late 2028.

Square feet
1,000,000
200,000
815,000
29,500
21,000
2,500,000
117,000
600,000
300,000
58,895
708,482
89,200
185,604
39,010
10,600
18,000
6,500
198,989
350,000
119,000
230,998
400,000
572,538
28,000
73,240
1,200,000
65,000
43,005
225,000
207,000
1,100,000
54,000
1,400,000
986,387
66,000
250,000
315,000
784,000
194,704
332,623
519,022
272,000
26,800
254,775
376,080
378,486
65,194
92,700
1,937,712
322,317
270,000
409,178
562,746
1,900,000
783,516
486,000
402,006
420,000
504,280
174,000
406,108
750,000
201,000
65,000
68,300
65,000
14,000
695,000
321,954
471,374
1,334,953
94,600
16,000
143,000
169,219
427,389
101,000
165,000
505,000
55,162
218,842
195,489
367,000
584,916
678,980
1,175,741
336,465
3,800,000
724,000
18,251
442,000
1,000,000
360,000
347,500
74,836
900,000
37,370
32,244
Market Sectors
Architect
Populous
Corgan
Corgan
PGAL
Woods Bagot
Perkins&Will
Wiss, Janney, Elstner Associates, Inc.
Perkins&Will
MKA / Arcadis
Herzog de Meuron / Stantec
Ratcliff
SOM
Mithun
Skidmore, Owings, & Merrill
Wolcott Architecture
Interior Architects
HNTB Architects
HKS
Solomon, Cordwell, Buenz & Associates
Skidmore, Owings, & Merrill, Mark Cavagnero Associates
Gayner Engineers.
Valerio Dewalt Train Associates
San Francisco Public Utilities Commission
HKS, Woods Bagot, ED2 International, KYA JV, Tsao Design Group
Woods Bagot and Interior Architects
Perkins+Will
Pelli Clarke Pelli Architects
HOK
Woods Bagot TSAO Design Group a joint venture
EHDD Architecture, Snohetta
HGA
NBBJ, ARUP
NBBJ
Harley Ellis Devereaux
Gensler, Harley Ellis Devereaux
Gensler
GBD Architects, Shimoda Design Group
Studio Gang
Skidmore, Owings & Merrill
Cuningham Group Architecture
Gensler
Architects Orange, BCV Architecture + Interiors
Hornberger+Worstell, ED2 International
Skidmore, Owings & Merrill
Perkins+Will
HNTB, STUDIOS Architecture
CallisonRTKL
Perkins+Will
Gensler
Gensler
Skidmore, Owings, & Merrill
GBD Architects, House & Robertson Architects
Mark Cavagnero Associate, Stantec
Valerio Dewalt Train Associates
Pei Cobb Freed, Gensler Architects, HED
HKS
Watry Design
HOK
HOK
HOK
HOK
HOK
Gensler
Mister Important Design, Shapery Enterprises
RMW Architecture & Interiors
Dowler Gruman Architects
Minert Architects
Gicklhorn Lazzaratto Partners (now Stantec)
Carrier Johnson
David Baker Architects
AC Martin
LARGE Architecture, Marmol Radziner & Associates
Handel Architects
Perkins+Will
BAR Architects
Form4 Architecture, El Dorado
Vasquez Marshall Architects, TranSystems, Watry Design
Gensler
Aston Pierra & Associates
Solomon, Cordwell, Buenz & Associates
Mark Cavagnero Associates
Jensen Design Architects.
BAR Architects
M.W. Steele Group Inc.
HKS
Ankrom Moisan Associates
Heller-Manus Achitects, Arquitectonica
David Baker, Christiani Johnson Architects
BKF Engineers, Langan Treadwell Rollo
HOK
Blitz Architects
Fong & Chan Architects
HKS Architects
Perkins+Will
SmithGroupJJR
Vasquez Marshall Architects
HDR Architecture, Herzog de Meuron World Itd. (HdM)
Skidmore, Owings & Merrill
HOK
Services Performed
Components
Delivery Method
Certifications
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